Uses and synthesis methods of Afoxolaner
Oral dewormer for dogs The new generation of oral dewormer for dogs (NexGard) (general name: Afoxolaner Chewable tablet) is the first oral dewormer for dogs that can kill both tick and flea parasites in China. Nicin belongs to the isoxazoline family, which by inhibiting GABA chloride ion channels, makes the nerves of arthropods highly excited and leads to death, and is a revolutionary powerful insecticide. August 28, 2017, Beijing - Boehringer Ingelheim, the world's second largest animal health company, announced the launch in China of NexGard, an oral dewormer for dogs targeting both flea and tick parasites. Nixin is a new generation of Chemicalbook isoxazoline in vitro deworming drug for dogs, with rapid effect, high safety, oral convenience and delicious taste, it will lead a new "food" generation of in vitro deworming. Niacin kills fleas quickly and has a longer lasting effect. Tests have proved that two hours after taking the drug to start killing fleas, 6 hours can kill 100% of fleas. Flea killing is extremely rapid, fleas can not lay eggs, avoiding environmental pollution, and can last five weeks 100% to prevent flea spawning. At the same time, Nixin's cicada-killing effect is fast and long-lasting. It can kill 8 common cicadas and insects, and the effect lasts for more than 1 month. It can kill 100% of the blood fanocephalus and shoulder cicada within 24 hours. It can kill more than 90% of ixodes in 24 hours, and the effect lasts for more than 4 weeks.
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