| Customization: | Available |
|---|---|
| Shape: | Injection |
| Transport Package: | Box |
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Gamithromycin Injection
Appearance: This product is a colorless to pale yellow clear liquid.
Pharmacological effects:
Pharmacology: Macrolide antibiotics. Kamimycin is a semi synthetic nitrogen-containing ester with a 15 membered ring, mainly binding to the 50S subunit of bacterial ribosomes to prevent peptide chain elongation and inhibit bacterial protein synthesis. In vitro experimental data shows that kanamycin has antibacterial effects on bovine hemolytic Manella, Pasteurella multocida, porcine pleuropneumoniae actinomycetes, Pasteurella multocida, and Haemophilus parasuis. The 7a position of the kanamycin lactone ring is an alkylated nitrogen, which can be rapidly absorbed under physiological pH conditions and maintained for a long time in the lung tissue of target animals.
Pharmacokinetics: A single dose of 6mg/kg body weight subcutaneous injection of streptomycin was administered to the neck of cattle, and the maximum blood drug concentration was reached within 30-60 minutes with a bioavailability greater than 98% and no gender differences. In vitro plasma protein binding studies showed a free drug concentration of 74%. The apparent distribution volume is 25L/kg. Gamma mycin can reach its maximum concentration in the lungs in less than 24 hours, and a lung/plasma concentration ratio greater than 264 indicates that gamma mycin can be rapidly absorbed into target tissues to combat respiratory diseases. The half-life of blood medicine is long (>2 days). The drug is mainly excreted in its original form through bile.
A single dose of 6mg/kg body weight intramuscular injection of streptomycin was administered to the neck of pigs, and the maximum blood drug concentration was reached within 5-10 minutes with a bioavailability greater than 92%. The in vitro plasma protein binding assay showed a free drug concentration of 77%. The apparent distribution volume is 39L/kg. Gamma mycin can be rapidly absorbed into target tissues to combat respiratory diseases. The concentration of kanamycin in the lungs is much higher than that in the blood, and the half-life of the drug in the blood is long (about 4 days). The drug is mainly excreted in its original form through bile.
Indications:
Used for the treatment of bovine respiratory diseases caused by Brucella hemolytica, Pasteurella multocida, and Mycoplasma that are sensitive to kanamycin; Porcine respiratory diseases caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, and Haemophilus parasuis.
Usage and dosage:
Calculated based on the addition of streptomycin. Subcutaneous injection: One dose, 6mg per 1kg body weight for cattle (equivalent to 1ml per 25kg body weight injection). The administration volume of each injection site shall not exceed 10ml. Intramuscular injection: One dose, 6mg per 1kg body weight for pigs (equivalent to 1ml per 25kg body weight injection). The administration volume of each injection site shall not exceed 5ml.
Adverse reactions:
When injecting this product under cowhide or into pig muscle, there may be brief swelling at the injection site, occasionally accompanied by mild pain.
Matters needing attention:
1. Prohibited for animals allergic to macrolide antibiotics.
2. It is prohibited to use it together with other macrolides or lincolamine antibiotics.
3. Prohibited for lactating cows.
4. Prohibited for pregnant cows with a due date within 2 months.
5. This product has not undergone safety assessment for pregnant sows. Please use it according to the risk assessment of the veterinarian.
6. Kamimycin may be irritating to the eyes and/or skin, and contact with the skin and/or eyes should be avoided. If accidentally touched, rinse immediately with water.
7. If accidentally injected into the human body, seek medical attention immediately and provide the label or instructions of this product to the doctor.
8. Wash hands after use.
9. Keep out of reach of children.
10. The bottle is valid for 28 days after opening, and any unused parts after expiration will be discarded.
Rest period for medication:
Cattle on the 64th, pigs on the 27th.
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1. What is the MOQ?
A: Our MOQ varies depending on the product. Generally, MOQs for regular pet products start at 100 pieces. For customized products, the MOQ may be higher. Please contact our sales team for the latest information.
2. Do you support customized service?
A: Yes, we provide customized service, including but not limited to product color, size, packaging and logo printing. Please contact our customer service team to discuss your specific needs and we will do our best to meet your requirements.
3. What are the payment methods?
A: We accept a variety of payment methods, including Trade Assurance, Bank Transfer, Letter of Credit (L/C), Western Union, and so on. Specific payment methods can be determined according to the order amount and mutual agreement. For the first time cooperation, we usually require 70% prepayment, and the rest is paid before shipment.
4. What is the logistics and delivery schedule?
A: We work with a number of logistics companies to ensure fast and safe delivery of goods around the world. The exact delivery time depends on the destination and the mode of transportation (air, sea, etc.). Normally, the delivery time for standard orders is 3-4 weeks after the order is placed, and the exact time will be informed when the order is confirmed.
5. What about quality assurance and after-sales service?
A: We strictly follow the international quality standards for production and conduct strict quality inspection before each batch of products leave the factory. We provide technical support and customer service to ensure customer satisfaction.
6. How to get samples?
A: You can request samples through our official website or by contacting a sales representative directly. The cost of samples and shipping fees are determined on a case-by-case basis. For new customers working together for the first time, we may charge a sample fee, which is refundable or creditable for subsequent bulk orders.
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