| Customization: | Available |
|---|---|
| CAS No.: | 13647-35-3 |
| Formula: | C20h27no3 |
|
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Tralostan can inhibit the synthesis of corticosteroids in the process of 3 β- Dehydrogenase, which reduces the synthesis of cortisol and aldosterone, is clinically used to treat Cushing's syndrome (hypercortisolemia) and primary Chemicalbook aldosteronism. However, the efficacy of treating Cushing's syndrome (hypercortisolemia) is not as good as that of metoprolone. This product also has a significant effect on reducing blood testosterone levels, which may be related to inhibiting its synthesis.
| Tests |
SPECIFICATIONS |
RESULTS |
| Appearance |
White or off-white Powder |
Off-white Powder |
| Identification |
The infrared absorption spectrum is concordant with the reference spectrum of standard. |
Complies |
| The retention time of the major peak of the test solution should be consistent with the retention time of the major peak of the reference solution. |
Complies |
|
| Loss on drying |
≤0.5% |
0.05% |
| Melting Point |
257ºC-270ºC |
258.0ºC-260.2ºC |
| Heavy Metals |
≤20ppm |
Complies |
| Specific Optical Rotation |
+137°~+139° |
+138.0° |
| Max Single Impurity |
≤0.5% |
0.22% |
| Residual Solvent | Ethanol ≤0.5% |
0.015% |
| Dichloromethane ≤0.06% |
Not detected |
|
| Tetrahydrofuran ≤0.5% |
Not detected |
|
| DMF ≤0.088% |
0.020% |
|
| Assay |
≥99% |
99.63% |
| Conclusion |
The results conform to the Enterprise standard. | |
Jinan Hongkongda Chemical Co., Ltd. is a technology driven enterprise focused on chemical raw materials and advanced pharmaceutical intermediates. The company is headquartered in Jinan, as the capital of Shandong Province, a major pharmaceutical province in China, with strong resource advantages. The company has a complete production management system, and the corresponding production base has more than 150 sets of reaction equipment, covering various special reaction production facilities such as high temperature, ultra-low temperature, and hydrogenation. Equipped with an experienced R&D team and established long-term stable cooperative relationships with numerous institutions, in order to continuously innovate and optimize processes. In order to optimize global resources, protect the environment, and make up for the shortage of some chemical intermediates in China, the company has established a cooperation center in India to develop domestically scarce varieties. Over the years, it has established stable cooperative relationships with multiple Indian enterprises and solved the problem of some product supply shortages.
1. The product quality can be guaranteed, and the quality is guaranteed
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