Medetomidine Hydrochloride Manufacturer CAS: 86347-15-1 100% Safe Pass Customs

• CAS No.: 86347-15-1
• Formula: C13h17cln2
• EINECS: 645-306-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: 99%
• Colour: White
• Product Packaging: Foil Pouches
• Melting Point: 164-166°c
• Storage Conditions: Sealed in Dry, Room Temperature
• Molecular Weight: 236.74
• Transport Package: Cartons
• Specification: 1kg
• Trademark: Hong Kongda
• Origin: Jinan
• Production Capacity: 500kg Per Year

Product Description

Product Description

Medetomidine HCl is a selective α2-adrenoceptor (α2-adrenoceptor) agonist with a Ki of 1.08 nM, which is 1620-fold more selective than acting on α1-adrenoceptor.

Medetomidine is a selective α2-adrenal receptor agonist with a Ki of 1.08 nM, 1620-fold selectivity over α1-adrenal receptors, and has little or no binding to other neurotransmitter receptors.

In anesthetized rats, medetomidine (1-100 μg/kg, intravenously) causes a dose-dependent transient decrease in blood pressure and heart rate. In brain-destroying spinal cord rats, medetomidine showed potent vasopressor (PD501.7 μg/kg) and sympathetic inhibition (ID501.6 μg/kg) without affecting the basal heart rate. Medetomidine causes a dose-dependent sedative effect, at high doses (>100 mcg / kg), causes a loss of positive reflexes, and lowers body temperature. Medetomidine causes a decrease in biogenic amine turnover in the brain, dose-dependent inhibition of norepinephrine (NE) inversion, inhibition of cerebral dopamine turnover at high doses, and decrease of serotonin reversal.

Medetomidine HCl is a selective α2-adrenoceptor (α2-adrenoceptor) agonist with a Ki of 1.08 nM, which is 1620-fold more selective than acting on α1-adrenoceptor.
 

Tests	SPECIFICATIONS	RESULTS
Appearance	Off-white to white powder	White powder
Identification	Chemical identification	Complies
	Infrared spectrometry	Complies
	Chloride identification	Complies
pH	3.5-4.5	4.27
Related substances	≤1.0%	0.029%
Loss on drying	≤1.0%	0.08%
Residue on ignition	≤0.1%	0.05%
Heavy metals	≤10ppm	Complies
Clarity and color of solution	Clear and colorless,if there is the turbidity and color, less than turbidity-1 and yellow-1	Less than turbidity-1; colorless
Residual solvent	Methanol≤0.3%	N.D.
	Acetone≤0.5%	N.D.
	Dichloromethane≤0.06%	0.032%
	Tetrahydrofuran≤0.072%	N.D.
	Ethyl acetate≤0.5%	0.060%
Assay (on dried basis)	≥99.0%	99.49%
Conclusion	The results conform to the Enterprise standard.

 

Packaging & Shipping

About Us

Jinan Hong Kongda Chemical Co., Ltd. is a high-tech enterprise specializing in the production of chemical raw materials and advanced pharmaceutical intermediates integrating scientific research, production and sales. The headquarter is located in Jinan, the capital of Shandong Province with major pharmaceutical province in China which has strong resource advantages.

The company has a complete production system with more than 150 sets of reaction equipment, covering production facilities for various special reactions such as high temperature, ultra-low temperature and hydrogenation. In order to continuously innovate and optimize the process, the company is equipped with an experienced R&D team, and established long-term and stable cooperative relations with many colleges and research institutes.

In order to optimize global resources, protect the environment, and make up for the shortage of some domestic chemical intermediates, the company has established a cooperation center in India to solve domestic shortages.

"Stable quality, price advantage" is our consistent service tenet, and has won a good reputation in the industry′s customer cooperation and service. We hope and look forward to cooperating with you in the future!

FAQ

Q1  Can i get some samples
A1  Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2  How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3  How to confirm the Product Quality before placing orders
A3  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q4  What's your MOQ
A4  Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5  How about delivery leadtime
A5  Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6  Is there a discount
A6  Different quantity has different discount.
Q7  How do you treat quality complaint
A7  First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8  How to contact us
A9  You can chat with us by Trademanager,Skype, Wechat, Whatsapp Online.
       You can choose your interested products and send inquiry to us.
       You can dial our telephone directly or send Email to us., you will get our reply.