Felocoxib CAS: 189954-96-9 Veterinary Drug Used for Anti-Inflammatory and Analgesic Purposes

• Customization: Available
• CAS No.: 189954-96-9
• Formula: 189954-96-9
• Model NO.: 99%
• EINECS: 200-001-2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Fusing Point: 78-80°c
• Boiling Point: 563.9±50.0 °c(Predicted)
• Density: 1.31
• Storage Condition: Normal Temperature
• Product Packaging: Aluminum Foil Bag
• Transport Package: Cardboard Bucket
• Specification: 1kg
• Trademark: Hong Kongda
• Origin: Shangdong Province
• Production Capacity: 500kg Per Year

Product Description

Summarize
Fecoxib is an important non-steroidal anti-inflammatory drug for animal use. Its main effect is to selectively inhibit the synthesis of COX-2 mediated prostaglandin, so as to block the conversion of arachidonic acid into prostaglandin, and then produce antipyretic, analgesic and anti-inflammatory effects. Compared with other non-steroidal anti-inflammatory veterinary drugs, felocoxib can efficiently and selectively inhibit COX-2, and can be quickly absorbed by the body, and has a significant effect on relieving osteoarthritis pain.

 

Biological activity
Firocoxib(ML1785713) is a potent, selective, orally active COX-2 inhibitor with an IC50 of 0.13μM. Firocoxib is 58 times more selective to COX-2 than to COX-1 (IC50 is 7.5μM). Firocoxib has anti-inflammatory properties.

 

Pharmacodynamics
Firocoxib is a non-steroidal anti-inflammatory drug that exerts antipyretic, analgesic and anti-inflammatory effects by selectively inhibiting cyclooxygenase-2 (COX-2) -mediated prostaglandin synthesis. In whole blood tests in dogs in vitro, the selectivity of felocoxib to COX-2 was about 380 times that of COX-1.

 

Product Name	Feloxoxib
CAS No.	189954-96-9