| Customization: | Available |
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| Shape: | Tube |
| Transport Package: | Box |
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Selamectin and Sarolaner Drops
Composition: Selamectin and Sarolaner
Appearance: Colorless to yellow transparent liquid.
Pharmacological effect:
Pharmacodynamics: Selamectin is a semi-synthetic compound of avermectins, which can make parasite neurons long-lasting superpolar by activating and/or enhancing glutamate-mediated chloride channel (GluCl) in invertebrates changes, disrupting its normal neurotransmission, resulting in paralysis, death or expulsion of the worm.
Sarolaner is an isoxazoline compound, mainly by blocking the γ-aminobutyric acid-mediated chloride ion channel (GABACl) in the central nervous system of insects and acarids, so as to prevent the influx of chloride ions, and nerve stimulation triggers nerve excitation increase, resulting in the death of the parasite.
Selamectin and Sarolaner have different mechanisms of action on GluCl and GABACl respectively, but the two will not interfere pharmacologically, selamectin exerts a functional blocking effect, and sarollana exerts a channel activity blocking effect , and synergistically destroy the nerve and muscle tissue functions of invertebrates, making the anthelmintic activity enhanced. Therefore, this product has a broad-spectrum anthelmintic effect, and can prevent and control internal and external parasites in cats.
Pharmacokinetics: The mean bioavailability of selamectin and Sarolaner are 40.5% and 57.9%, respectively, and can be distributed systemically. Selamectin and Sarolaner have long half-lives in cats, 12.5 days and 41.5 days, respectively. In cats, selamectin is mainly eliminated in the feces as the original form, and salolana is mainly eliminated in the unchanged form through the bile and feces.
Indication:
Ø For the treatment and prevention of cat flea infection, auxiliary treatment of allergic dermatitis caused by fleas;
Ø Treating tick, ear mite, and lice infestation in cats;
Ø Treat feline roundworm and hookworm infections;
Ø Prevent feline heartworm disease.
Usage and dosage:
Cats 8 weeks of age and above, weighing 1.25kg and above.
Calculated by Selamectin and Sarolaner. External application: one dose, per 1kg of body weight, for cats, 6mg of selamectin and 1mg of sarolaner, administered once a month.
| Cat weight (kg) | Specifications and dosage | ||
| 0.25 mg | 0.5 mg | 1 mg | |
| 1.25 ≤ Weight ≤2.5 | 1 tablet | ||
| 2.5 < weight ≤ 5 | 1 tablet | ||
| 5 < weight ≤ 10 | 1 tablet | ||
| Weight > 50 | Select the right combination of specifications for administration | ||
Adverse reactions:
1. This product may cause mild and temporary itching at the medication site.
2. In a few cases, this product may cause mild to moderate hair loss, erythema and animal salivation at the medication site.
Shelf life: 2 years.
Specification:
(1)0.25ml: 15mg+2.5mg (2)0.5ml: 30mg+5mg (3)1.0ml: 60mg+10mg
Packaging:50 tablets/bottle
Storage:Sealed and stored in a dry place below 30C.
Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 10000box. But usually we accept less quantity such as 1000box on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A8 You can chat with us by Trademanager,Skype, Wechat, Whatsapp Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us, you will get our reply.
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