R'aloxifene Hydrochloride is an estrogen agonist/antagonist called selective estrogen receptor modulator (SERM), belonging to the benzothiohydride group. The biological action of R'aloxifene is mediated primarily by binding to the estrogen receptor. This binding results in the activation of the estrogen pathway in some tissues (agonism) and the blocking of the estrogen pathway in others (antagonism).
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1) R 'aloxifene is used to prevent and treat osteoporosis (a condition in which bones become thin, weak and easily broken) in menopausal women (life changes, end of menstrual period). R 'aloxifene is also used to reduce the risk of invasive breast cancer (breast cancer that has spread beyond the breast ducts or lobules into the surrounding breast tissue) in women at high risk of developing such cancers or having osteoporosis. R 'aloxifene cannot be used to treat invasive breast cancer or prevent recurrence in women who already have invasive breast cancer.
(2) R 'aloxifene also cannot be used to reduce the risk of non-invasive breast cancer. R 'aloxifene belongs to a class of drugs called selective estrogen receptor modulators (SERM). R 'aloxifene prevents and treats osteoporosis by mimicking the effects of estrogen (a female hormone produced by the body) to increase the density (thickness) of bones. R 'Aloxifene reduces the risk of invasive breast cancer by blocking the effect of estrogen on breast tissue. This may prevent the development of tumors that require estrogen to grow.
(3)Raloxifene hydrochloride is a non-steroidal selective estrogen receptor modulator (SERM). Anti-osteoporosis. Treatment of postmenopausal osteoporosis. Insoluble in water.
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