Medetomidine Intermediates CAS: 86347-14-0 Security Clearance

• CAS No.: 86347-14-0
• Formula: C13h16n2
• EINECS: 1592732-453-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: 99%
• Colour: White
• Product Packaging: Foil Pouches
• Boiling Point: 381.9±11.0 °c(Predicted)
• Density: 1.053
• Storage Conditions: Sealed in Dry, Room Temperature
• Transport Package: Cardboard Boxes
• Specification: 1kg
• Trademark: Hong Kongda
• Origin: Jinan
• Production Capacity: 500kg Per Year

Product Description

Appearance	white powder
Total impurities	0.44%
Max single impurity	0.21%
Loss on drying	0.13%
Residue on ignition	0.04%
Assay	99.56%

Dexmedetomidine is a highly selective α2-adrenergic receptor agonist with sedative, hypnotic, analgesic, antisympathetic and other effects, and is widely used in clinical anesthesia and sedation in intensive care units. Due to the characteristics of dexmedetomidine inducing similar to physiological sleep, low respiratory depression and strong neuroprotective effect, coupled with the development of anesthetics and sleep medicine in recent years, dexmedetomidine is increasingly used in the diagnosis and treatment of sleep disorders.

Dexmedetomidine is a highly selective α2-adrenergic receptor agonist that produces corresponding pharmacological effects by acting on α2 receptors in the central nervous system and peripheral nervous system. Dexmedetomidine produces sedative-hypnotic effect by acting on the α2 receptor of the coegalus nucleus and activating the endogenous pro-sleep pathway, so that the patient can maintain the natural sleep state of non-REM stage III, which is characterized by the fact that the person suffering from Chemicalbook can be aroused by stimulation or language, and there is no respiratory depression during the sedation-hypnosis process. Dexmedetomidine also has anxiolytic, stress reduction, hemodynamic stabilization, analgesia, inhibition of salivary gland secretion, anti-chilling and diuretic effects. In addition, dexmedetomidine has a good synergistic effect when combined with other sedative and analgesic drugs, which can significantly reduce the amount of other sedative and analgesic drugs.

Product Description