CAS No.: | 1093861-60-9 |
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Formula: | C26h17clf9n3o3 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Colour: | White |
Samples: |
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Customization: |
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NexGard (commonly known as Afurana Chewable Tablets) is the first oral deworming drug for dogs in China that can kill both ticks and fleas. Nixin belongs to the imidazoline family, which inhibits the GABA chloride ion channel, causing high nerve excitability and death in arthropods. It is a revolutionary and potent insecticide. On August 28, 2017, Beijing - Boehringer Ingelheim, the world's second-largest animal health company, announced the launch of its canine oral deworming drug NexGard (commonly known as Affrana Chewable Tablets) for fleas and ticks in China. Nixixin is a new generation of isoxazoline based in vitro insecticidal drugs for dogs. It has the characteristics of fast onset, high safety, convenient oral administration, and delicious taste. It will lead the new generation of in vitro insecticidal drugs. Nicosin can quickly kill fleas and has a more long-lasting effect. Experiments have shown that killing fleas starts two hours after taking medication, and can kill 100% of fleas within six hours. Flea killing is extremely rapid, and fleas are unable to lay eggs, avoiding environmental pollution. It can last for five weeks and 100% prevent flea spawning. At the same time, Nixin's cicada killing effect is fast and long-lasting. It can drive and kill 8 common cicada insects, and the effect lasts for more than a month. It can kill 100% of the blood red fan head alcohol and shoulder hard cicada within 24 hours. It can kill more than 90% of tick mites within 24 hours, and the efficacy lasts for more than 4 weeks.
Tests |
SPECIFICATIONS |
RESULTS |
Appearance |
White to off-white powder |
White powder |
Solubility |
Very soluble in N,N-Dimethylformamide,free soluble in methanol,practically insoluble in water |
Complies |
NMR |
Match with Structure |
Complies |
MS |
[M+H]+ [M+NH4]+ [M+Na]+ [M-H]- [M-H+H2O]- |
[M+H]+ [M-H]- |
Related substances | Purity of HPLC NLT 99.0% |
99.46% |
Any Individual Impurity,NMT 0.20% |
0.14% |
|
Heavy Metals |
≤10ppm |
Complies |
Water |
≤ 1.0% |
0.70% |
Residue on ignition |
≤ 0.1% |
0.03% |
Residual Solvent | Ethyl acetate ≤0.5% |
N.D |
Tetrahydrofuran≤0.072% |
N.D |
|
Acetonitrile≤0.041% |
N.D |
|
Dichloromethane≤0.06% |
N.D |
|
Methanol≤0.3% |
N.D |
|
Toluene≤0.089% |
N.D |
|
Isopropanol≤0.5% |
0.20% |
|
Assay |
Content:98.0% to 102.0% (anhydrous substance) |
99.23% |
Conclusion |
The results conform to the enterprise standard. |
Jinan Hongkongda Chemical Co., Ltd. is a technology driven enterprise focused on chemical raw materials and advanced pharmaceutical intermediates. The company is headquartered in Jinan, as the capital of Shandong Province, a major pharmaceutical province in China, with strong resource advantages. The company has a complete production management system, and the corresponding production base has more than 150 sets of reaction equipment, covering various special reaction production facilities such as high temperature, ultra-low temperature, and hydrogenation. Equipped with an experienced R&D team and established long-term stable cooperative relationships with numerous institutions, in order to continuously innovate and optimize processes. In order to optimize global resources, protect the environment, and make up for the shortage of some chemical intermediates in China, the company has established a cooperation center in India to develop domestically scarce varieties. Over the years, it has established stable cooperative relationships with multiple Indian enterprises and solved the problem of some product supply shortages.
1. The product quality can be guaranteed, and the quality is guaranteed
2. There is a one-on-one sales manager service that can provide technical support
3. Provide quality inspection documents, physical images, liquid chromatography, testing methods, and competitive prices
4. The company has an advantage in inventory and spot goods, and can provide bulk goods at kilogram prices and tonnage
5. Contract making - Contract signing by both parties - Corporate payment - Issuance of 13% value-added tax invoice - Express package shipping - Timely delivery - Real time follow-up of goods - After sales consultation
6. Protecting the legitimate rights and interests of customers is our mission, and quality and service are our unchanging pursuits
7. Long term cooperation with scientific research units in universities such as Beijing, Shanghai, Shenzhen, Xiamen, Guangzhou, Tianjin, Anhui, Chongqing, Changsha, Shenyang, etc
8. Exporting to North America, Central/South America, Western Europe, Eastern Europe, Oceania, Africa and other regions
Q1:Are you trading company or manufacturer?
A1:We are chemical factory in China. So we can provide wholesale price.
Q2:How can I get the samples?
A2:We can provide you sample for our existing products, the lead time is about 1-5 days.You just need to pay the sample fee.
Q3:Is there a discount?
A3:Different quantity has different discount.
Q4:Can you provide relevant documents?
A4:Of course. We can provide Commercial Invoice, Packing List, Bill of loading, COA and Origin certificate.
Q5:Do you accept third party inspection?
A5:Yes.we do.
Q6:How long is your delivery time?
A6:Generally it is with 7 days if the goods are in stock. According to quantity your required,the delivery time may slightly change.
Q7:What's your terms of payment?
A7:We can accept various payment methods, L/C, T/T, Paypal, Western Union etc.
Q8:How do you treat quality complaint ?
A8:First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
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