Broad-spectrum antifungal agents for dermatology
Terbinafine hydrochloride is a broad spectrum antifungal drug used in dermatology. It was developed by Swiss pharmaceutical company Novartis in the 1980s and first launched in the UK in 1991. In 1996, it was approved by the United States FDA as an OTC drug and was listed in the United States in the same year. Currently, it is sold in more than 90 countries around the world. It can specifically disturb the late biodegradation of fungal sterols, selectively inhibit the activity of fungal squalene cycoperoxidase, and block the epoxidation reaction of squalene in the process of fungal cell membrane formation, so as to achieve the role of killing or inhibiting fungi. It is suitable for the treatment of skin candidiasis, such as ringworm of hand, tinea pedis, jock itch, tinea corporis and tinea versicolor, and is also the best medicine for the treatment of gray nails.
indication
1. Skin, hair and nail infection caused by trichophyton albus, Trichophyton palpitum, Trichophyton verrucosum, Trichophyton severum and Trichophyton purpura, etc., microspora Canis and Epidermophyton floccus.
2. Various ringworm diseases (tinea corporis, jock itch, tinea pedis and tinea capitis, etc.) and skin yeast infections caused by candida albicans.
3. Onychomycosis caused by mold (onychomycosis infection).
use
Terbinafine hydrochloride is a broad-spectrum antifungal agent, which has significant curative effect on athlete's foot, nail, tinea corporis, tinea corporis and tinea versicolor caused by fungi. It can also be used for bronchial asthma, asthmatic bronchitis and emphysema.
| Product name |
Terbinafine HCl |
| CAS |
78628-80-5 |
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