Product Description
Levodropropizine is a chiral antitussive drug first launched by Dompe'Farm in Italy, which inhibits the cough reflex by acting on the C-fibers in the respiratory tract, and is clinically used for the treatment of dry cough without phlegm, compared with other existing antitussive drugs, this product is a peripheral antitussive drug, which has almost no effect on the central system, it has good selectivity, strong antitussive effect, and no drowsiness, respiratory depression, Dependence and other side effects, it has fewer side effects as compared to racemates.
In rats, the central sedative effect of levodropropizine is weaker than that of racemic tartrate, and it does not cause physical dependence. Levodropropizine (15 mg/kg, intravenously) simultaneously reduces the duration of asphyxia and the response of C-fibers to phenyl biguanide. LVDP-induced inhibition of C-fiber response to PBG is averaged 50% in pulmonary fibers and 25% in non-pulmonary fibers. Levodropropizine has been shown to have good antitussive activity in anesthetized guinea pigs and rabbits. In guinea pigs and rabbits with mechanically and electrically induced cough, the activity of levodropropizine (intravenously) is 1/10 to 1/20 that of , while similar to hydroxypropiperazine. Levodropropizine (oral chemicalbook) is similar to hydroxyproproziine and in the treatment of cough caused by irritating aerosols. Levodropropizine (40 mcg/50 μl, i.c.v.) There is no effect on electrically induced cough, whereas (5 mcg/50 μL, i.c.v.) Significantly prevents coughing in guinea pigs. Levodropropizine has a secondary site of action, which is associated with sensory neuropeptides. In rat trachea, Levodropropizine (10 mg/kg, 50 mg/kg, as well as 200 mg/kg) dose-dependently reduces capsaicin-induced spillage of Evansblue dye. Levodropropizine (200 mg/kg) inhibits extravasation of substance P, but it does not affect platelet-activating factor-induced extravasation.
| Molecular Weight |
236.315 |
| Density |
1.168 |
| Refractive Index |
1.57 |
| Specification |
98% |
Packaging & Shipping
About Us
Jinan Hong Kongda Chemical Co., Ltd. is a high-tech enterprise specializing in the production of chemical raw materials and advanced pharmaceutical intermediates integrating scientific research, production and sales. The headquarter is located in Jinan, the capital of Shandong Province with major pharmaceutical province in China which has strong resource advantages.
The company has a complete production system with more than 150 sets of reaction equipment, covering production facilities for various special reactions such as high temperature, ultra-low temperature and hydrogenation. In order to continuously innovate and optimize the process, the company is equipped with an experienced R&D team, and established long-term and stable cooperative relations with many colleges and research institutes.
In order to optimize global resources, protect the environment, and make up for the shortage of some domestic chemical intermediates, the company has established a cooperation center in India to solve domestic shortages.
"Stable quality, price advantage" is our consistent service tenet, and has won a good reputation in the industry′s customer cooperation and service. We hope and look forward to cooperating with you in the future!
FAQ
Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A9 You can chat with us by Trademanager,Skype, Wechat, Whatsapp Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us., you will get our reply.
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